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古朵生物:姜黄素对胃癌的抗肿瘤活性
发布时间:2019-05-05   点击次数:115次

JIANGHUANGSUBEIGUANGFANYONGYUFUYUSHIWUYANSEHEWEIDAO,DANKEXUEJIAMENFAXIAN,ZHEIZHONGLAIZIJIANGHUANGZHIWU(JIANGHUANG)DEHUANGSEFENMOYEKEYIBANGZHUYUFANGHUODUIKANGWEIAI。

SHENGBAOLUOLIANBANGDAXUE(UNIFESP)HEBAXILIANBANGDAXUE(UFPA)YANJIURENYUANDEYANJIUFAXIAN,ZHEIZHONGSESUHESHIWUZHONGFAXIANDEQITASHENGWUHUOXINGHUAHEWUDUIWEIAIDEZHILIAOXIAOGUOKENENGSHIDISANHEDIWUBAXINANXINGHENVXINGDEAIZHENGLEIXING。

该研究是圣保罗研究基金会 - FAPESP支持的主题项目的一部分。其研究结果发表在Epigenomics期刊上。“我们对有可能预防或治疗胃癌的所有营养素和生物活性化合物的科学文献进行了大量审查,发现姜黄素就是其中之一,”UFPA教授Danielle Queiroz Calcagno是该研究的作者,告诉。

GENJULAIZIFAPESPJIANGXUEJINZAIUNIFESPJINXINGBOSHIHOUYANJIUDECalcagnoBIAOSHI,DANGUCHUN(YIZHONGWEISHENGSUD),BAILILUCHUN(DUOFEN)HEHUPISUDENGHUAHEWUKEYIYUFANGHUODUIKANGWEIAI,YINWEITAMENSHIZUDANBAIHUOXINGDETIANRANDIAOJIEJI。

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彩搜网ZHEIXIEDANBAIZHIZHONGANJISUANLIANDEFANYIHOUHUAXUEXIUSHI,LIRUYIXIANHUA(YIXIANJIDEYINRU)HUOJIAJIHUA(TIANJIAJIAJI),KEYIYINGXIANGRANSEZHIYASUOBINGYINCIYINGXIANGJIYINBIAODA。

“LIRU,RUGUOZUDANBAIBEIYIXIANHUA,RANSEZHIJIUHUININGJUDEGENGSHAO,BINGQIEKEYIBIAODAQINEIBUDNAPIANDUANQUYUDEJIYIN。XIANGFAN,RUGUOZUDANBAIMEIYOUYIXIANHUA,RANSEZHIJIANGHUIGENGJIANONGSUO,JIYINBUHUIBEIBIAODA,“CalganoJIESHISHUO。

JINNIANLAIJINXINGDEYANJIUBIAOMING,FANYIHOUZUDANBAIXIUSHIDAOZHIJIYINBIAODADEGAIBIANERBUYINGXIANGDNAXULIE。ZHEIXIEBIAOGUANYICHUANBIANYIYINGXIANGBUTONGLEIXINGAIZHENGDEFAZHAN。

WEILEQUEDINGZHEIYIJIASHESHIFOUYESHIYONGYUWEIAI,YOUUNIFESPJIAOSHOUMaríliadeArruda Cardoso SmithXIEDIAODEJIZUYANJIURENYUANYANJIULELAIZIJIANKANGGETIHEZHENDUANHUANYOUWEIAIDEHUANZHEDEWEIXIBAOYANGPINZHONGDEZUDANBAIYIXIANHUAMOSHI。

彩搜网YANJIURENYUANFAXIAN,LAIZIWEIAIHUANZHEDEXIBAOBIAOXIANCHUZUDANBAIYIXIANZHUANYIMEI(HATs)HEZUDANBAITUOYIXIANMEI(HDACs)BIAODAMOSHIDEGAIBIAN。ZHEIXIEGAIBIANSHIBIAOGUANYICHUANDEBINGQIEYINGXIANGXUDUOZHONGLIU(BAOKUOWEIAI)ZHONGJIYINZUDEJIEGOUHEWANZHENGXING。

YINWEIJINDEYANJIUHAIBIAOMINGYINGYANGSUHESHENGWUHUOXINGHUAHEWUKEYIDIAOJIEHATHEHDACDEHUOXING,UNIFESPHEUFPADEKEXUEJIAMENKAISHIFAXIANRENHEKENENGYINGXIANGZUDANBAIYIXIANHUADEYINSU,CONGERYOUZHUYUYUFANGWEIAI,SHENZHIZHILIAOZHEIZHONGJIBING。

彩搜网CHUJIANGHUANGSUWAI,QITAZAIDIAOJIEZUDANBAIHUOXINGZHONGQIGUANJIANZUOYONGDEHUAHEWUHAIYOUDANGAIHUACHUN,BAILILUCHUN(ZHUYAOCUNZAIYUPUTAOZIHEHONGPUTAOJIUZHONG),HUPISU(FENGFUDEPINGGUO,XILANHUAHEYANGCONG),garcinol(CONGSHUPIZHONGFENLICHULAI)。 kokum tree,Garcinia indica)HEDINGSUANNA(YOUCHANGDAOXIJUNTONGGUOSHANSHIXIANWEIFAJIAOCHANSHENG)。

“ZHEIXIEHUAHEWUKETONGGUOCUJINHUOYIZHIZUDANBAIYIXIANHUALAICUJINHUOYIZHICANYUWEIAIFAZHANDEJIYIN,”CalcagnoSHUO。

LIRU,JIANGHUANGSUZHUYAOTONGGUOYIZHIHATHEHDACLAIYIZHIAIXIBAOZENGZHIBINGYOUDAOXIBAODIAOWANG(CHENGXUXINGXIBAOSIWANG),CONGERYINGXIANGZUDANBAIXIUSHI。GarcinolDEHUAXUEJIEGOULEISIYUJIANGHUANGSU,KEYIZHIHAT,BINGTONGGUOZHONGHEZIYOUJILAIYUFANGWEIAI。

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